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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ea0bd7cc5f1989bd77c30847c05c06fcaaa36ce80e7d5c8c374680832348c3' 
  AND token = 'karCoYg5TuSH5dDy22La8laj4Ztb3yZFemZ20cK7P9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}