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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f33e08131c041702335865fd0e9c5de59d477a90316ff9cf976790b283b4a07' 
  AND token = '/NSAS+Cnde+xT6qwM+xvH5r4d/LkJBrAFjxhsh3D3P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}