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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b13648786f1cae93380d1ff496da70e531e43f3b6c0ca4a3ab942c45cf9020' 
  AND token = '+Cl5de65mrR3UpJqmN1zutTe1yjvUkRIlMotSW3Nq6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}