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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9d0a82724922e36c10eb2c603bc57a5e1f97185eb87cbd668c59534677a8a9b' 
  AND token = 'aXDRpP3+ojPG7IxbxrYjMJb5IfIdpu8irLaX+rVQLl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}