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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd95386377d8aec1a11abb06b6f5c50006a10d5194d9ffe1e9ebcbb89b6d3bc42' 
  AND token = '17LoWqpzRDUkypDnOFtzlG2xXCNrNyAfWo6c1ph4Uh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}