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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f817f095dcd6504e0a7074bdcc9deb3081664ce348dbbe80af1e576e2d9b9de' 
  AND token = 'sqdpbhE0zQEX16X1mN0jz4ykm31Iu3qQm6aUZGDZGSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}