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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48eaa4b31c23d6902a48b2a75d2c22791fa3f741613ae53d3a9bf535884fdc5e' 
  AND token = 'oyzupQ1uPnHLgkiqOl2dZrHr8O4AzWSpUlPtFL1IT+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}