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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f3baff2046198e0dd8331c1afbc97c840f340c4dffd8c4c0ec25e7b5627e2c' 
  AND token = 'A9N1kPtOF6w4+Tlg2VD+zmEOuFNyvuQxktkS07V7Mig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}