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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '166983bcd2bc32f5c337ab31e714e52de351e78a1073b8cf6185d8a009ed5cf4' 
  AND token = 'vgP9YR2vaZqg9I9OWJNPlQpC80h4Mrw33+ApcCm66SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}