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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c24a5d04ee53c09f8f18c87b4c305c775a6e757c436aeed18f58f4ce75e7690d' 
  AND token = 'jGdeGn2jz/1lCF5AHQSH3IB6RYCrTUSxuXd9Zbyjnf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}