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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0caef62ff5c872da912ec674e7273256abcf3fb1c7ee0c3d792e1f3aa0dde41' 
  AND token = 'I0+GGYBQVG/pDHX7ECu+rRZERwnWB4JfVU5Mrz4uN6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}