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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86257714aadda4736ceb125b8d62e8fc5296cb8c73e59395fe578ac3239d56d8' 
  AND token = 'Z7o4kL0h+RN1mUgONvEERwrMEwW3EpFWqd0yZvzY9yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}