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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35864e28e2789f38f532ec02231891ff199fa81f8602ff188dadb10e70c5420' 
  AND token = 'Qu5NTV028ySsG/5XkcXAHdx3i5nerSEuVyXmx3zf3oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}