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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99a6c9287840f35ed0a456e01b88282632be6ed300b567655ff6a47a1bd8420d' 
  AND token = 'FQV5yzJzQaBJk+VRise+zHSMW/2i7rHV+Rwev3e7zjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}