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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7421344c6fbff841217a2cb3b70384907fb5ed807477cdc5f7b61d4a0722af2c' 
  AND token = 'T2+0d5b2zSk2V2XyC7jyXwCP6tgwDiI0s5+gVSRtTk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}