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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fce3b9889a90d6804dfc6c3b99d15acbdff8f5aaa9debf151a7bf13d08edd6b0' 
  AND token = 'OtHHtmH/W8UEiShmxc/lDc76wHMNHlXqlvMBefVeAHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}