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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d888375f2601a735ae6dad49322d3b756ef92ec5e473c02fd12c5a115071d3' 
  AND token = 'E6aufclYCsvCsddAm56FuK13xpRrU4M75zvqWV+kPPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}