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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b7f277893fc35ab2befbcc3e55dbda02f45d5c9302f91610c82d814925c386' 
  AND token = 'DHKpIlYUOx2fWK8rIxq518hIUrk1Qx/wooyWDFiN4LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}