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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186febb83f743ce5a2b82ef31efe7b8d72b95927313855d22771fe5028582b51' 
  AND token = '4kAr8dpj05oTEUvejy/xtdt/r1e15D7j3H+boUi1aWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}