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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53741265ff422e485064ee34b711ef382664cba5e23b1dd0cf337e4702ef2982' 
  AND token = 'PVFHH53M4UEkkpvu2ail1HSnJKY62bjF3GWh8XvpuVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}