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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f485033fd1797446ce66f64e779f0d08ab36b61c355745149509fb3603e4b342' 
  AND token = '7kGUUl6Gonq67lCUkkejE/H4z4ifz4GTvvSQ/EQLJTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}