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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc3b74db62694535c3edd3876d7ee76a1263d9967b97720c7bac245a4f24f9a1' 
  AND token = 'QR8PByUI0Jekz9wlk/3BRHIB/Q1ltiWbru6kUJx9ycA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}