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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c19e1360bf111c59c507748fec77022a649faec078ffba5dae3e3ed624331336' 
  AND token = 'v05Q+9sMSvSt2+HxGUN7+inOkzuve7v4Rx63J5fUtG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}