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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ab73b2d6d0363add5bc487e09c7b6880d43919c3a20e2a884c6793760b964e' 
  AND token = '1OKU2B6zkrK4rV/dClELxk0f5OfA0yd5He273ahKczE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}