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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654c0b30994015932324c52693ddbe5553ee1e9793d507bf457db099c52b1271' 
  AND token = 'nUy2pmbxIIue3fD2CQkwFdMz2YhKZUl3xiw6K0zKv6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}