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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fd2e4267bb4c6ca2ae29038812ec3e886706893fe150588e321486050057ce' 
  AND token = 'hpBGbQGf1h5irQH0F0tLXlSlNi4/SgLNd++wlXZX5pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}