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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea2e6f253b021f2dc9af3fed6ca66f33340b21e444251061c9aaaaca9cdf161e' 
  AND token = 'CuBtIZQi7x2gJLRT70skSIaKvm6C7+Td0AfldNK6Qdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00101

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}